Doença Óssea de Paget
diagnóstico e terapêutica
DOI:
https://doi.org/10.24220/2318-0897v1a1992e1443Palavras-chave:
Doença Ós pea de Paget , osteodistrofla deformame, diagnóstico e tratamentoResumo
.Os autores apresentam uma atualização dos conceitos relacionados à etiopatogenia, diagnóstico clínico e exames subsidiários, diagnóstico diferencial , tratamento e prognóstico da doença óssea de Paget . Apresentam as principais características clínicas e radiológicas em 42 pacientes seguidos nas disciplinas de Reumatologia da FCM-UNICAMP e da Universidade Federal do Rio Grande do Sul . Discutem as eventuais complicações e as principais perspectivas terapêuticas.
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Referências
ACAR, J.; DELBARRE, F.; WA YNEBERGER, N. Les complications cardiovasculairesde la malad.ie osseuse de Paget. Arch. Mal. Couer. Vaiss, 61:849, 1968.
ALTMAN, R. D.; BROWM, M.; GARGANO, F. How Back Pain in Paget's desease of bone. Clin. Orthop. Re/ated Dis., 217:152, 1987.
ALTMAN, R. D. & COLLINS, B. Muscoleskeletal manifestations of Paget's disease of bone. Arch. Rheumat., 23:121, 1980.
ALTMAN, R. D.; JOHNSTON, e.e.; KHAIRI, M.R.A.; WELLMAN, H.; SERAFINI, A.N.; SANKEY, R.R. Influence of d.isodium etidronate on clinicai and laboratory manifestations of Paget's disease of bone. N. Eng/. J. Med., 289:1379, 1973.
BARR Y, H. C. Orthopedic aspects of Paget's disease of bone. Arch. Rheumat., 23:1, 128, 1980.
BURCKHARDT, P.M.; SINGER, F.R.; POTIS, J.T. Parathyroid function in patients with Paget's d.isease treated with salmon calcitonin. Clin. Endocrinol., 2:15, 1973.
CARNEIRO, R.A. Doença de Paget. In: CRUZ FILHO, Clíni- ca reumatológica. Rio de Janeiro, Guanabara Koogan, 1980, p.469.
CARNEIRO, R.A. Tratamento da doença de Paget com calcitonina de salmão. Arg. Bras. Méd. 61:4, 1987.
CHEUNG, H.S. Collagen biosynthesis by bones in Paget's d.isease. Clin. Res., 25:154, 1977.
DE ROSE, J.; SINGER, F.R.; AVRAMIDES, A. Response of Paget's d.isease to porcine and salmon calcitonins. Effects of long term treatment. AmJ.Med., 56:858, 1974.
DOVE, J. Complete factures ofthe femur in Paget's d.isease ofbone. J.Bonejoint Surg., 62B(l):12, 1980.
FRANCIS, M.J & SMITH, R. Evidence of generalized connective tissue defect in Paget's dlse'àse ofbone. Lancet, 1:841, 1974.
HARRISON, C.V. & LENNOX, B. Heart block in osteite deformans. Br. Heart J., 10:167, 1948.
HIOCO, D.J. La maladie de Paget. 5. ed. St. Paul de Vence, Laboratoires Armour Montagn, 1981.
HOWELL, D.S. Metabolic bone diseases. ln. MCCARTY, D.J. Arthristis and allied cond.ictions. 9, ed. Philadelphia, Lea & Febiger, 1979, p. 1313.
KRANE, S.M. Etidronate disodium in the treatment of Paget disease of bone. Ann. lnt. Med., 96:619, 1982.
KRANE, S.M. Urinary excretions of hidroxylyzine and its glycosides as an índex of collagen degradation. J. Clin. /nvest. 59:819, 1977.
MARQUES NETO, J. F.; BRENOL, J. e. T.; MÜLLEN, e.V.; ROCHA, M.C.; SAMARA, A.M. Doença óssea de Paget. Orientação diagnóstica. Rev. Bras. Reuma/. (23):3, 1983.
MARQUES NETO, J.F.; BRENOL, J.C.T.; MÜLLEN, C.A;. SAMARA, A.M. Orientação diagnóstica na doença óssea de Paget. Rev. Bras. Reumatol., 23(3): l05, 1983.
MEUNIER, P.J. Bone histomorphometry in Paget's desease. Quantitative and dynamic analysis of pagetic and nonpagetic bane tissue. Arthr. Rheumat., 23:1095, 1980.
MEUNIER, P.J.; SALSON, C.; MATHIEU, L.; CHAPUY, M.C.; DELAMS, P.; ALEXANDRE, C.; CHARMON, S. Skeletal d.istribution and biochemical parameters of Paget's disease. Clin. Orthop. Re/ated dis. 217:37, 1987.
MILLS, B.G. & SINGER, F.R. Nuclear inclusions in Paget's disease ofbone.Science 194:201, 1976.
MILLS, B.G. & SINGER, F.R. Clinicai evoluation of virai antigen data in Paget's disease of bone. Clin. Orthop. re/ated dis., 217:16, 1987.
MIRRA, J.M. Pathogenesis of Paget's disease based on virai ethiology. Clin. Orthop. related dis., 217:162, 1987.
MOORE, S. Osteitis deformans. A theory of its etiology.J. Bane Joint Surg., 33A:421, 1951.
MURPHY, W.A.; WHITE, M.P.; & HADDAD, J.G. Paget bane d.isease radiologic documentation of healing with human calcitonin therapy. Radiology 136:1, 1980.
NICOLLE, M.H.; DUDOGNON, P.; REVEL, M., NICK, J. Faut-il encore opére les paraplégies pagétiq4_es. Rev. Neuro/., Paris, 135(2):153, 1979.
PAGET, J. On a form of chronic inflammation of bones (osteitis deformans). Med. Cir. Trans. 760:37, 1877.
RASMUSSEN, H. & BORDIER, P. Toe physiological and cellular basis of metaboLic bone diseases. Baltimore, Willians & Wilkin, 1974. p. 847.
REBEL, A. Bane tissue in Paget's disease ofbone, ultrastructure and imunocitology. Arth. Rheum,. 23:1104, 1980.
REBEL, A. Les inclusions de ostéoclastes dans la maladie osseuse de Paget. Rev. Rheum., 42:637, 1975.
REBEL, A.; MALKANI, K. BASLÉ, M.; BREGEON, C. Osteoclast ultraestructurein Paget's disease. Clin. Orthop. Related Dis. 217:4, 1987.
REBEL, A. Osteoclast ultraestructure in oPaget's disease. Calei[ Tissue Res., 20:187, 1976.