Melhora das funções executivas em pessoas com transtorno por uso de substâncias

o papel do treinamento funcional intervalado de alta intensidade

Autores/as

Palabras clave:

Transtornos relacionados ao uso de substâncias, Usuários de drogas, Funções executivas, Treinamento físico, Exercício físico

Resumen

Objetivo
Pessoas com transtorno de uso de substâncias apresentam capacidade cognitiva comprometida pelos prejuízos nas funções executivas. Vinte minutos de exercício aeróbio moderado ou de força promoveu melhora na capacidade cognitiva dessas pessoas, contudo, não há uma padronização de tipo, programa, intensidade, duração e frequência. Este estudo avaliou o exercício funcional de alta intensidade sobre as funções executivas de pessoas com tal transtorno.
Método
Quarenta pacientes foram alocados nos grupos: Intervenção (N = 22) e Controle (N = 18), e, avaliados, antes e após uma sessão aguda de treinamento funcional de alta intensidade ou de um período de repouso, respectivamente.
Resultados
O grupo Intervenção melhorou: capacidade cognitiva, desempenho na flexibilidade mental, controle inibitório, memória de trabalho e respostas perceptuais positivas para esforço e afeto (“Clarear a Mente”, “Facilitar a Caminhada”) em comparação com o grupo Controle. Os resultados sugerem que esta intervenção pode ser uma alternativa terapêutica acessível, funcional e afetivamente positiva.

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Ai, J.-Y., Chen, F.-T., Hsieh, S.-S., Kao, S.-C., Chen, A.-G., Hung, T.-M., & Chang, Y.-K. (2021). The effect of acute high-intensity interval training on executive function: a systematic review. International Journal of Environmental Research and Public Health, 18(7), 3593. https://doi.org/10.3390/ijerph18073593

Arney, B. E., Glover, R., Fusco, A., Cortis, C., de Koning, J. J., van Erp, T., Jaime, S., Mikat, R. P., Porcari, J. P., & Foster, C. (2019). Comparison of RPE (Rating of Perceived Exertion) Scales for Session RPE. International Journal of Sports Physiology and Performance, 14(7), 994-996. https://doi.org/10.1123/ijspp.2018-0637

Associação Brasileira de Empresas de Pesquisa. (2020). Critério de Classificação Econômica Brasil: alterações na aplicação do Critério Brasil, válidas a partir de 01/09/2020. ABEP. https://www.abep.org/criterio-brasil

Bechara, A., Damasio, H., & Damasio, A. R. (2000). Emotion, decision making and the orbitofrontal cortex. Cerebral Cortex, 10(3), 295-307. https://doi.org/10.1093/cercor/10.3.295

Ben-Zeev, T., & Okun, E. (2021). High-intensity functional training: molecular mechanisms and benefits. Neuromolecular Medicine, 23, 335-338. https://doi.org/10.1007/s12017-020-08638-8

Ben-Zeev, T., Hirsh, T., Weiss, I., Gornstein, M., & Okun, E. (2020). The effects of High-intensity Functional Training (HIFT) on spatial learning, visual pattern separation and attention Span in adolescents. Frontiers in Behavioral Neuroscience, 14. https://doi.org/10.3389/fnbeh.2020.577390

Broyd, S. J., van Hell, H. H., Beale, C., Yücel, M., Solowij, N. (2016). Acute and chronic effects of cannabinoids on human cognition: a systematic review. Biological Psychiatry, 79(7), 557-567. https://doi.org/10.1016/j.biopsych.2015.12.002

Brown, R. A., Abrantes, A. M., Read, J. P., Marcus, B. H., Jakicic, J., Strong, D. R., Oakley, J. R., Ramsey, S. E., Kahler, C. W., Stuart, G. G., Dubreuil, M. E., & Gordon, A. A. (2010). A pilot study of aerobic exercise as an adjunctive treatment for drug dependence. Mental Health and Physical Activity, 3(1), 27-34. https://doi.org/10.1016/j.mhpa.2010.03.001

Cabral, D. A., Costa, K. G., Okano, A. H., Elsangedy, H. M., Rachetti, V. P., & Fontes, E. B. (2017). Improving cerebral oxygenation, cognition and autonomic nervous system control of a chronic alcohol abuser through a three-month running program. Addictive Behaviors Reports, 6, 83-89. https://doi.org/10.1016/j.abrep.2017.08.004

Cabral, D., Tavares, V., Costa, K., Nascimento, P., Faro, H., Elsangedy, H., & Fontes, E. (2018). The benefits of high intensity exercise on the brain of a drug abuser. Global Journal of Health Science, 10(6), 123. https://doi.org/10.5539/gjhs.v10n6p123

Chang, Y. K., Labban, J. D., Gapin, J. I., & Etnier, J. L. (2012). The effects of acute exercise on cognitive performance: a meta-analysis. Brain Research, 1453, 87-101. https://doi.org/10.1016/j.brainres.2012.02.068

Connor, J. P., Gullo, M. J., White, A., & Kelly, A. B. (2014). Polysubstance use: Diagnostic challenges, patterns of use and health. Current Opinion in Psychiatry, 27(4), 269-275. https://doi.org/10.1097/YCO.0000000000000069

Cristofori, I., Cohen-Zimerman, S., & Grafman, J. (2019). Executive functions. Handbook of Clinical Neurology, 163, 197-219. https://doi.org/10.1016/B978-0-12-804281-6.00011-2

Da Costa, K. G., Barbieri, J. F., Hohl, R., Costa, E. C., & Fontes, E. B. (2017). Exercise training improves cardiorespiratory fitness and cognitive function in individuals with substance use disorders: a pilot study. Sport Sciences for Health, 13(2), 437-441. https://doi.org/10.1007/s11332-016-0338-1

Ebbeling, C. B., Ward, A., Puleo, E. M., Widrick, J., & Rippe, J. M. (1991). Development of a single-stage submaximal treadmill walking test. Medicine and Science in Sports and Exercise, 23(8), 966-973.

Feito, Y., Heinrich, K. M., Butcher, S. J., & Poston, W. S. C. (2018). High-Intensity Functional Training (HIFT): definition and research implications for improved fitness. Sports, 6(3), 76. https://doi.org/10.3390/sports6030076

Feltenstein, M. W., See, R. E., & Fuchs, R. A. (2021). Neural substrates and circuits of drug addiction. Cold Spring Harbor Perspectives in Medicine, 11(4), a039628. https://doi.org/10.1101/cshperspect.a039628

Ferreira, S. E., Santos, A. K. M., Okano, A. H., Gonçalves, B. S. B., & Araújo, J. F. (2017). Efeitos agudos do exercício físico no tratamento da dependência química. Revista Brasileira de Ciências do Esporte, 39, 123-131. https://doi.org/10.1016/j.rbce.2016.01.016

Friedman, N. P., & Robbins, T. W. (2022). The role of prefrontal cortex in cognitive control and executive function. Neuropsychopharmacology, 47(1), 72-89. https://doi.org/10.1038/s41386-021-01132-0

Gilson, N. D., Andersson, D., Papinczak, Z. E., Rutherford, Z., John, J., Coombes, J. S., & Brown, W. J. (2023). High intensity and sprint interval training, and work-related cognitive function in adults: a systematic review. Scandinavian Journal of Medicine & Science in Sports, 33(6), 814-833. https://doi.org/10.1111/sms.14349

Gomes-Oliveira, M. H., Gorenstein, C., Lotufo Neto, F., Andrade, L. H., & Wang, Y. P. (2012). Validation of the Brazilian Portuguese version of the Beck Depression Inventory-II in a community sample. Brazilian Journal of Psychiatry, 34, 389-394. https://doi.org/10.1016/j.rbp.2012.03.005

Hardy, C. J., & Rejeski, W. J. (1989). Not what, but how one feels: the measurement of affect during exercise. Journal of Sport and Exercise Psychology, 11(3), 304-317. https://doi.org/10.1123/jsep.11.3.304

Henrique, I. F. S., De Micheli, D., Lacerda, R. B., Lacerda, L. A., & Formigoni, M. L. O. de S. (2004). Validation of the Brazilian version of Alcohol, Smoking and Substance Involvement Screening Test (ASSIST). Revista da Associação Médica Brasileira, 50(2), 199-206. https://doi.org/10.1590/S0104-42302004000200039

Hobkirk, A. L., Bell, R. P., Utevsky, A. V., Huettel, S., & Meade, C. S. (2019). Reward and executive control network resting-state functional connectivity is associated with impulsivity during reward-based decision making for cocaine users. Drug and Alcohol Dependence, 194, 32-39. https://doi.org/10.1016/j.drugalcdep.2018.09.013

Huang, J., Zheng, Y., Gao, D., Hu, M., & Yuan, T. (2020). Effects of exercise on depression, anxiety, cognitive control, craving, physical fitness and quality of life in methamphetamine-dependent patients. Frontiers in Psychiatry, 10. https://doi.org/10.3389/fpsyt.2019.00999

Kessels, R. P., van Zandvoort, M. J., Postma, A., Kappelle, L. J., & de Haan, E. H. (2000). The Corsi block-tapping task: standardization and normative data. Applied Neuropsychology, 7(4), 252-258. https://doi.org/10.1207/S15324826AN0704_8

Khandekar, P., Shenoy, S., & Sathe, A. (2022). Prefrontal cortex hemodynamic response to acute high intensity intermittent exercise during executive function processing. The Journal of General Psychology, 150(3), 1-28. https://doi.org/10.1080/00221309.2022.2048785

Lezak, M. D., Howieson, D. B., Loring, D. W., Hannay, H. J., & Fischer, J. S. (2004). Neuropsychological assessment (4th ed). Oxford University Press.

Linke, S. E., Hovsepians, R., Schnebly, B., Godfrey, K., Noble, M., Strong, D. R., Isgro, M., & Lindamer, L. A. (2019). The Go-VAR (Veterans Active Recovery): an adjunctive, exercise-based intervention for veterans recovering from substance use disorders. Journal of Psychoactive Drugs, 51(1), 68-77. https://doi.org/10.1080/02791072.2018.1560518

Liu, Y., van den Wildenberg, W. P. M., Graaf, Y., Ames, S. L., Baldacchino, A., Bø, R., Cadaveira, F., Campanella, S., Christiansen, P., Claus, E. D., Colzato, L. S., Filbey, F. M., Foxe, J. J., Garavan, H., Hendershot, C. S., Hester, R., Jester, J. M., Karoly, H. C., Kräplin, A., … Wiers, R. W. (2019). Is (poly-) substance use associated with impaired inhibitory control? A mega-analysis controlling for confounders. Neuroscience & Biobehavioral Reviews, 105, 288-304. https://doi.org/10.1016/j.neubiorev.2019.07.006

Matumoto, P. A., & Rossini, J. C. (2013). Avaliação das funções atentivas e flexibilidade mental em dependentes químicos. Psicologia: Reflexão e Crítica, 26(2), 339-345. https://doi.org/10.1590/S0102-79722013000200014

Merege Filho, C. A. A., Alves, C. R. R., Sepúlveda, C. A., Costa, A. S., Lancha Junior, A. H., Gualano, B., Merege Filho, C. A. A., Alves, C. R. R., Sepúlveda, C. A., Costa, A. S., Lancha Junior, A. H., & Gualano, B. (2014). Influência do exercício físico na cognição: uma atualização sobre mecanismos fisiológicos. Revista Brasileira de Medicina do Esporte, 20(3), 237-241. https://doi.org/10.1590/1517-86922014200301930

Norgan, N. G. (1988). A Review of: “Anthropometric Standardization Reference Manual”. Edited by T. G. LOHMAN, A. F. ROCHE and R. MARTORELL. (Champaign, IL.: Human Kinetics Books, 1988.) [Pp. vi+ 177.] £28•00. ISBN 087322 121 4. Ergonomics, 31(10), 1493-1494. https://doi.org/10.1080/00140138808966796

Novkovic, T., Mittmann, T., & Manahan-Vaughan, D. (2015). BDNF contributes to the facilitation of hippocampal synaptic plasticity and learning enabled by environmental enrichment. Hippocampus, 25(1), 1-15. https://doi.org/10.1002/hipo.22342

Olds, J., & Milner, P. (1954). Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain. Journal of Comparative and Physiological Psychology, 47(6), 419-427. https://doi.org/10.1037/h0058775

Park, S.-Y., & Schott, N. (2022). The immediate and sustained effects of exercise-induced hemodynamic response on executive function during fine motor-cognitive tasks using functional near-infrared spectroscopy. Journal of Integrative Neuroscience, 21(3). https://doi.org/10.31083/j.jin2103098

Periáñez, J. A., Lubrini, G., García-Gutiérrez, A., & Ríos-Lago, M. (2021). Construct validity of the Stroop colorword test: influence of speed of visual search, verbal fluency, working memory, cognitive flexibility, and conflict monitoring. Archives of Clinical Neuropsychology, 36(1), 99-111. https://doi.org/10.1093/arclin/acaa034

Schlegel, P. (2020). CrossFit® Training strategies from the perspective of concurrent training: A systematic review. Journal of Sports Science & Medicine, 19(4), 670-680.

Severinsen, M. C. K., & Pedersen, B. K. (2020). Muscle-organ crosstalk: the emerging roles of myokines. Endocrine Reviews, 41(4), 594-609. https://doi.org/10.1210/endrev/bnaa016

Sharma, V., Singh, T. G., Kaur, A., Mannan, A., & Dhiman, S. (2023). Brain-derived neurotrophic factor: a novel dynamically regulated therapeutic modulator in neurological disorders. Neurochemical Research, 48(2), 317-339. https://doi.org/10.1007/s11064-022-03755-1

Siddi, S., Preti, A., Lara, E., Brébion, G., Vila, R., Iglesias, M., Cuevas-Esteban, J., López-Carrilero, R., Butjosa, A., & Haro, J. M. (2020). Comparison of the touch-screen and traditional versions of the Corsi blocktapping test in patients with psychosis and healthy controls. BMC Psychiatry, 20(1), 329. https://doi.org/10.1186/s12888-020-02716-8

Solinas, M., Belujon, P., Fernagut, P. O., Jaber, M., & Thiriet, N. (2019). Dopamine and addiction: what have we learned from 40 years of research. Journal of Neural Transmission, 126(4), 481-516. https://doi.org/10.1007/s00702-018-1957-2

Teixeira, R. V., Batista, G. R., Mortatti, A. L., Dantas, P. M. S., & Cabral, B. G. A. T. (2020). Effects of six weeks of high-intensity functional training on physical performance in participants with different training volumes and frequencies. International Journal of Environmental Research and Public Health, 17(17), 6058. https://doi.org/10.3390/ijerph17176058

Tian, S., Liang, Z., Qiu, F., & Wang, X. (2023). Physical activity on executive function in sedentary individuals: systematic review and meta-analysis of randomized controlled trials. PloS One, 18(12), e0294251. https://doi.org/10.1371/journal.pone.0294251

Tibana, R. A., Sousa, N. M. F., Cunha, G. V., Prestes, J., Fett, C., Gabbett, T. J., & Voltarelli, F. A. (2018). Validity of session rating perceived exertion method for quantifying internal training load during high-intensity functional training. Sports, 6(3), 68. https://doi.org/10.3390/sports6030068

Tsai, C.-L., Wang, C.-H., Pan, C.-Y., Chen, F.-C., Huang, T.-H., & Chou, F.-Y. (2014). Executive function and endocrinological responses to acute resistance exercise. Frontiers in Behavioral Neuroscience, 8, 262. https://doi.org/10.3389/fnbeh.2014.00262

United Nations Office on Drugs and Crime. (2022). World Drug Report 2022. United Nations. https://www.unodc.org/res/wdr2022/MS/WDR22_Booklet_1.pdf

Vaughan, S., Morris, N., Shum, D., O’Dwyer, S., & Polit, D. (2012). Study protocol: a randomised controlled trial of the effects of a multi-modal exercise program on cognition and physical functioning in older women. BMC Geriatrics, 12, 60. https://doi.org/10.1186/1471-2318-12-60

Vaughan, S., Wallis, M., Polit, D., Steele, M., Shum, D., & Morris, N. (2014). The effects of multimodal exercise on cognitive and physical functioning and brain-derived neurotrophic factor in older women: a randomised controlled trial. Age and Ageing, 43(5), 623-629. https://doi.org/10.1093/ageing/afu010

Volkow, N. D., & Blanco, C. (2023). Substance use disorders: A comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention. World Psychiatry, 22(2), 203-229. https://doi.org/10.1002/wps.21073

Volkow, N. D., Michaelides, M., & Baler, R. (2019). The Neuroscience of drug reward and addiction. Physiological Reviews, 99(4), 2115-2140. https://doi.org/10.1152/physrev.00014.2018

Wang, D., Zhou, C., Zhao, M., Wu, X., & Chang, Y.-K. (2016). Dose-response relationships between exercise intensity, cravings, and inhibitory control in methamphetamine dependence: an ERPs study. Drug and Alcohol Dependence, 161, 331-339. https://doi.org/10.1016/j.drugalcdep.2016.02.023

Wilke, J. (2020). Functional high-intensity exercise is more effective in acutely increasing working memory than aerobic walking: an exploratory randomized, controlled trial. Scientific Reports, 10, 1-7. https://doi.org/10.1038/s41598-020-69139-z

Xue, B., Waseem, S. M. A., Zhu, Z., Alshahrani, M. A., Nazam, N., Anjum, F., Habib, A. H., Rafeeq, M. M., Nazam, F., & Sharma, M. (2022). Brain-derived neurotrophic factor: a connecting link between nutrition, lifestyle, and alzheimer’s disease. Frontiers in Neuroscience, 16, e925991. https://doi.org/10.3389/fnins.2022.925991

Yin, Y., Yang, S., Xiao, K., Wang, T., Wang, J., Schöllhorn, W. I., Zhu, D., & Pang, X. (2022). Comparison of the acute effects of Tai chi versus high-intensity interval training on inhibitory control in individuals with substance use disorder. Frontiers in Psychology, 13, 941719. https://doi.org/10.3389/fpsyg.2022.941719

Zhang, R., & Volkow, N. D. (2019). Brain default-mode network dysfunction in addiction. NeuroImage, 200, 313-331. https://doi.org/10.1016/j.neuroimage.2019.06.036

Publicado

2025-11-19

Cómo citar

dos Santos, C. J., Mazaro-Costa, R., & Ferreira, S. E. (2025). Melhora das funções executivas em pessoas com transtorno por uso de substâncias: o papel do treinamento funcional intervalado de alta intensidade. Estudos De Psicologia, 42. Recuperado a partir de https://puccampinas.emnuvens.com.br/estpsi/article/view/11565

Número

Sección

PSICOLOGIA COGNITIVA, PERCEPÇÃO E NEUROCIÊNCIA