Branched-Chain amino acids intake is negatively related to body adiposity in individuals at cardiometabolic risk
Keywords:
Cardiovascular diseases, Feeding behavior, Isoleucine. Leucine, Overweight, ValineAbstract
Objective
To assess the relationship between branched-chain amino acids intake in the current diet and the metabolic and body adiposity markers in a population at cardiovascular risk.
Methods
This is a cross-sectional study with 282 adults and elderly people from the Cardiovascular Health Care Program of the Universidade Federal de Viçosa. Sociodemographic, anthropometric and body composition data, as well as metabolic biomarkers were collected using standardized protocols. Dietary intake of branched amino acids was assessed using a 24-hour recall.
Results
Individuals with a higher branched-chain amino acids intake (≥2.6g/day, median value) had lower body fat (29.6 vs 32.2%; p=0.019), and higher serum ferritin (113.2 vs. 60.1mg/dL; p=0.006) and uric acid concentrations (4.4 vs. 4.0; p=0.023). In addition, a lower prevalence of overweight and excessive abdominal fat (p<0.05) was found in the individuals with higher branched-chain amino acids intake. They also had a higher daily intake of fiber, copper, zinc, magnesium, and iron, as well as a lower intake of total lipids.
Conclusion
In the present study, the intake of branched amino acids is negatively related to total and central adiposity, but more studies are needed to fully elucidate this possible relationship. (Brazilian Registry of Clinical Trials, code RBR-5n4y2g).
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Copyright (c) 2023 Alinne Paula de ALMEIDA, Fernanda Santos FORTES, Brenda Kelly Souza SILVEIRA, Nínive de Almeida REIS, Helen Hermana Miranda HERMSDORFF
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