Nutritional status of children and adolescents survivors of acute lymphocytic leukemia treated at a reference center in Northeastern Brazil
Keywords:
Adolescent, Child, Lymphocytic leukemia, Obesity, Overweight, SurvivorAbstract
Objective
This study evaluated the nutritional status and clinical, laboratory, and behavioral factors associated with overweight among children and adolescents survivors of acute lymphocytic leukemia treated at a reference center in Northeastern Brazil.
Methods
A case-series study was carried out with 30 survivors of acute lymphocytic leukemia. Clinical, behavioral and laboratory data were collected between March and September 2011. The anthropometric variables height-for-age and body mass index-for-age were determined on three different occasions (time of diagnosis, end of treatment, and post-treatment period), using the reference standards of the World Health Organization.
Results
The mean age and standard deviation of the sample was 10.2±3.2 years. A total of 33.3% of the survivors were overweight at the beginning and end of treatment. In the post-treatment period, a significant increase was found in the body mass index-for-age Z-score. The frequency of excess weight was 43.3%. The frequency of abdominal obesity was 16.6% and 35.5% based on the waist circumference and waist-to-height ratio, respectively. The comparison of body mass index-for-age Z-scores before and after treatment revealed significantly stunted linear growth. The laboratory tests showed that total cholesterol was 52.1% above the upper limit. However, 58.3%, 66.7%, and 79.2% of the sample had high-density lipoprotein and low-density lipoprotein
cholesterol, and triglyceride levels, respectively, within the recommended ranges.
Conclusion
Based on the frequency of excess weight, abdominal obesity, and high total cholesterol, the study survivors of acute lymphocytic leukemia were at greater risk of developing chronic, non-communicable diseases.
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Copyright (c) 2023 Bianca Araújo de OLIVEIRA, Mecneide Mendes LINS, Francisco PEDROSA, Poliana Coelho CABRAL, Janine Maciel BARBOSA
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