Asymptomatic patients present infection related to the central venous catheter used for total parenteral nutrition
Keywords:
Infection, Catheter-related infections, Parenteral nutrition totalAbstract
Objective
The aim of this study was to evaluate the frequency of central venous catheter-related infections in hospitalized patients receiving total parenteral nutrition.
Methods
Central venous catheters were analyzed immediately after removal due to infection, hospital discharge or thrombosis. The patients with catheter-related infection were named Group 1 and the other patients were named Group 2.
Results
Eighteen patients were studied. There was no statistically significant difference in nutritional status between the two groups. A total of 28 catheters were analyzed. Sixty-eight percent of the catheters were infected: 72% of them were from Group 1 and 28% from Group 2 (asymptomatic patients). Systemic infection was diagnosed in 70% of the patients from Group 1. Positive blood culture was found in 17% of the patients from Group 2. The microorganisms found were: Staphylococcus sp. (48%), Candida sp. (21%), Enterococcus faecalis (16%), Pseudomonas aerurginosa (10%) and Proteus sp. (5%).
Conclusion
Central venous catheter infection is common in hospitalized asymptomatic patients. Patients receiving total parenteral nutrition are most frequently infected with Candida sp. Therefore, the creation of barriers that block colonization in the central venous catheter is essential to decrease the morbidity and mortality among patients that depend on total parenteral nutrition.
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References
Dudrick SJ, Wilmore DW, Vars HM, Rhoads JE. Long-term total parenteral nutrition with growth, development, and positive nitrogen balance. Surgery. 1968; 64(1):134-42.
Shils ME, Wright WL, Turnbull A, Brescia F. Long term parenteral nutrition through external arteriovenous shunt. N Engl J Med. 1970; 283(7): 341-4.
Ireton-Jones C, DeLegge M. Home parenteral nutrition registry: a five-year retrospective evaluation of outcomes of patients receiving home parenteral nutrition support. Nutrition. 2005; 21(2):156-60. doi:10.1016/j.nut.2004.04.024.
O’Keefe SJ, Buchman A, Fishbein T, Jeejeebhoy K, Jeppesen P, Shaffer J. Short bowel syndrome and intestinal failure: consensus definitions and overview. Clin Gastroenterol Hepatol. 2006; 4(1): 6-10. doi:10.1016/j.cgh.2005.10.002.
O’Keefe SJ, Burnes JU, Thompson RL. Recurrent sepsis in home parenteral nutrition patients: an analysis of risk factors. J Parenter Enteral Nutr. 1994; 18(3): 256-63. doi: 10.1177/0148607194018003256.
Caballero B. Global patterns of child health: the role of nutrition. Ann Nutr Metab. 2002; 46(1): S3-S7. doi: 10.1159/000066400.
Unamuno MRDL, Carneiro JJ, Chueire FB, Marchini JS, Suen VMM. Uso de cateteres venosos totalmente implantados para nutrição parenteral: cuidados, tempo de permanência e ocorrência de complicações infecciosas. Rev Nutr. 2005; 18(2): 261-9. doi: 10.1590/S1415-52732005000200010.
Colomb V, Fabeiro M, Dabbas M, Goulet O, Merckx J, Ricour C. Central venous catheter-related infections in children on long-term home parenteral nutrition: incidence and risk factors. Clin Nutr. 2000; 19(5):355-9. doi: 10.1054/clnu.2000.0132.
Veenstra DL, Saint S, Saha S, Lumley T, Sullivan SD. Efficacy of antiseptic-impregnated central venous catheter in preventing catheter-related bloodstream infection: a meta-analysis. JAMA. 1999; 281(3):261-7.
Sherertz RJ. Update on vascular catheter infections. Curr Opin Infect Dis. 2004; 17(4):303-7. doi: 10.1097/01.qco.0000136925.52673.16.
Centers for Disease Control and Prevention. Guidelines for the prevention of intravascular catheter-related infections. MMWR. 2002; 51(10): 1-34.
Beghetto MG, Victorino J, Teixeira L, Azevedo MJ. Parenteral nutrition as a risk factor for central venous catheter: related infection. J Parenter Enteral Nutr. 2005; 29(5):367-73. doi: 10.1177/0148607105029005367.
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Copyright (c) 2023 Juliana Deh Carvalho MACHADO, Vivian Marques Miguel SUEN, José Fernando de Castro FIGUEIREDO (in memorian), Júlio Sérgio MARCHINI
This work is licensed under a Creative Commons Attribution 4.0 International License.
