Metabolic acidosis in chronic kidney disease: the nutritional approach
Keywords:
Acidosis, Protein-energy malnutrition, Diet, Chronic kidney diseaseAbstract
Metabolic acidosis is a common manifestation of chronic kidney disease and is associated with increased protein catabolism, decreased protein synthesis and negative nitrogen balance. Diet strongly influences acid generation, determining the level of acidosis in chronic kidney disease patients. Some researchers have observed that it is possible to estimate renal net acid excretion, and the analysis of the renal acid load of selected, frequently consumed foods may allow an appropriate prediction of the effects of diet on metabolic acidosis. This article discusses the physiological bases as well as the clinical implications of acidosis in patients
with chronic kidney disease and the influence of the diet on the acid-base balance of these patients.
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Copyright (c) 2023 Viviane de Oliveira LEAL, Maurilo LEITE JÚNIOR, Denise MAFRA
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