Energetic metabolism in endurance athletes is different between sexes
Keywords:
foods for persons engaged in physical activities, endurance athletes, energy metabolism, sexAbstract
Endurance athletes have higher energy needs because they spend a lot of energy during exercise. However, the metabolic differences between genders and if these differences will imply in dietary changes are still not clear. Thus, the objective of this study was to gather information from the literature on the differences between the genders regarding energy metabolism in endurance athletes. Some studies show that during long-lasting exercise, women use more lipids and less carbohydrates and proteins as energy source when compared with men. Yet, other authors have not found a difference between genders in the proportions of metabolized substrates but in the kinds of lipids used. This difference in the use of substrates has been related with distinct
concentrations of some hormones in men and women, such as 17β-estradiol, progesterone, testosterone, epinephrine, norepinephrine, growth hormone, insulin and glucagon. It has also been observed that male athletes increase their glycogen stores when they consume diets with a high sugar load while females only increase their glycogen stores when they consume diets with a high sugar load and excess calories. This finding is very relevant since the concentration of glycogen is directly associated with the athlete’s performance during endurance exercise. Therefore, literature suggests that there are differences between the genders
regarding the use of substrates in athletes. However, new studies are needed to better clarify the energy metabolism of endurance athletes and thus make more adequate nutritional recommendations.
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References
Tarnopolsky LJ, MacDougall JD, Atkinson AS, Tarnopolsky MA, Sutton JR. Gender differences in substrate for endurance exercise. J Appl Physiol. 1990; 68(1):302-8.
Tarnopolsky MA, Atkinson AS, Phillips SM, MacDougall JD. Carbohydrate loading and metabolism during exercise in men and women. J Appl Physiol. 1995; 78(4):1360-8.
Tarnopolsky MA, Bosman M, MacDonald JR, Vandeputte D, Martin J, Roy BD. Postexercise protein-carbohydrate and carbohydrate supplements increase muscle glycogen in men and women. J Appl Physiol. 1997; 83(6):1877-83.
Horton TJ, Pagliassotti MJ, Hobbs K, Hill JO. Fuel metabolism in men and women during and after long-duration exercise. J Appl Physiol. 1998; 85(5):1823-32.
Carter SL, Rennie C, Tarnopolsky MA. Substrate utilization during endurance exercise in men and women after endurance training. Am J Physiol Endocrinol Metab. 2001; 280(6):E898-907.
McKenzie S, Phillips SM, Carter SL, Lowther S, Gibala MJ, Tarnopolsky MA. Endurance exercise training attenuates leucine oxidation and BCOAD activation during exercise in humans. Am J Physiol Endocrinol Metab. 2000; 278(4):E580-7.
Lamont LS, McCullough AJ, Kalhan SC. Gender differences in the regulation of amino acid metabolism. J Appl Physiol. 2003; 95(3):1259-65.
Knechtle B, Müller G, Willmann F, Kotteck K, Eser P, Knecht H. Fat oxidation in men and women endurance athletes in running and cycling. Int J Sports Med. 2004; 25(1):38-44.
Tarnopolsky MA. Gender differences in substrate metabolism during endurance exercise. Can J Appl Physiol. 2000; 25(4):312-7.
Venables MC, Achten J, Jeukendrup AE. Determinants of fat oxidation during exercise in healthy men and women: a cross-sectional study. J Appl Physiol. 2005; 98(1):160-7.
Phillips SM, Atkinson SA, Tarnopolsky MA, MacDougall JD. Gender differences in leucine kinetics and nitrogen balance in endurance athletes. J Appl Physiol. 1993; 75(5):2134-41.
Roepstorff C, Steffensen CH, Madsen M, Stallknecht B, Kanstrup I-L, Richter EA, et al. Gender differences in substrate utilization during submaximal exercise in endurance-trained subjects. Am J Physiol Endocrinol Metab. 2002; 282(2): E435-47.
Steffensen CH, Roepstorff C, Madsen M, Kiens B. Myocellular triacylglycerol breakdown in females but not in males during exercise. Am J Physiol Endocrinol Metab. 2002; 282(3):E634-42.
Goedecke JH, Gibson ASC, Grobler L, Collins M, Noakes TD, Lambert EV. Determinants of the variability in respiratory exchange ratio at rest and during exercise in trained athletes. Am J Physiol Endocrinol Metab. 2000; 279(6):E1325-34.
M’Kaouar H, Péronnet F, Massicotte D, Lavoie C. Gender difference in the metabolic response to prolonged exercise with [13C]glucose ingestion. Eur J Appl Physiol. 2004; 92(4-5):462-9.
Ruby BC, Coggan AR, Zderic TW. Gender differences in glucose kinetics and substrate oxidation during exercise near the lactate threshold. J Appl Physiol. 2002; 92(3):1125-32.
Perreault L, Lavely JM, Kittelson JM, Horton TJ. Gender differences in lipoprotein lipase activity after acute exercise. Obes Res. 2004; 12(2):241-9.
Perreault L, Lavely JM, Bergman BC, Horton TJ. Gender differences in insulin action after a single bout of exercise. J Appl Physiol. 2004; 97(3): 1013-21.
Romijn JA, Coyle EF, Sidossis LS, Rosenblatt J, Wolfe RR. Substrate metabolism during different exercise intensities in endurance-trained women. J Appl Physiol. 2000; 88(5):1707-14.
Tarnopolsky MA, Zawada C, Richmand LB, Carter S, Shearer J, Graham T, et al. Gender differences in carbohydrate loading are related to energy intake. J Appl Physiol. 2001; 91(1):225-30.
Tarnopolsky MA, Roy BD, MacDonald JP, Mckenzie S, Martin J, Ettinger S. Short-term 17-β-estradiol administration does not affect metabolism in young males. Int J Sports Med. 2001; 22(3): 175-80.
Roepstorff C, Donsmark M, Thiele M, Vistisen B, Stewart G, Vissing K, et al. Sex differences in hormone-sensitive lipase expression, activity, and phosphorylation in skeletal muscle at rest and during exercise. Am J Physiol Endocrinol Metab. 2006; 291(5):E1106-14.
Marliss EB, Kreisman SH, Manzon A, Halter JB, Vranic M, Nessim SJ. Gender differences in glucoregulatory responses to intense exercise. J Appl Physiol. 2000; 88(2):457-66.
Mittendorfer B, Horowitz JF, Klein S. Effect of gender on lipid kinetics during endurance exercise of moderate intensity in untrained subjects. Am J Physiol Endocrinol Metab. 2002; 283(1):E58-65.
Tarnopolsky MA, Ruby BC. Sex differences in carbohydrate metabolism. Curr Opinion Clin Nutr Metabol Care. 2001; 4(6):521-6.
Devries MC, Hamadeh MJ, Grahan TE, Tarnopolsky MA. 17β-estradiol supplementation decreases glucose rate of appearance and disappearance with no effect on glycogen utilization during moderate intensity exercise in men. J Clin Endocrinol Metab. 2005; 90(11):6218-25.
Hamadeh MJ, Devries MC, Tarnopolsky MA. Estrogen supplementation reduces whole body leucine and cabohydrate oxidation and increases lipid oxidation in men during endurance exercise. J Clin Endocrinol Metab. 2005; 90(6):3592-9.
Horton TJ, Grunwald GK, Lavely J, Donahoo WT. Glucose Kinetics differ between women and men, during and after exercise. J Appl Physiol. 2006; 100(6):1883-94.
Devries MC, Hamadeh MJ, Phillips SM, Tarnopolsky MA. Menstrual cycle phase and sex influence muscle glycogen utilization and glucose turnover during moderate-intensity endurance exercise. Am J Physiol Regul Integr Comp Physiol. 2006; 291(4): R1120-8.
Horton TJ, Miller EK, Bourret K. No effect of menstrual cycle phase on glycerol or palmitate kinetics during 90 min of moderate exercise. J Appl Physiol. 2006; 100(3):917-25.
Carter S, McKenzie S, Mourtzakis M, Mahoney DJ, Tarnopolsky MA. Short-term 17beta-estradiol decreases glucose Ra but not whole body metabolism during endurance exercise. J Appl Physiol. 2001; 90(1):139-46.
Kiens B, Roepstorff C, Glatz JFC, Bonen A, Schjerling P, Knudsen J, et al. Lipid-binding proteins and lipoprotein lipase activity in human skeletal muscle: influence of physical activity and gender. J Appl Physiol. 2004; 97(4):1209-18.
Riddell MC, Partington SL, Stupka N, Armstrong D, Rennie C, Tarnopolsky MA. Substrate utilization during exercise performed with and without glucose ingestion in female and male endurance trained athletes. Int J Sport Nutr Exerc Metab. 2003; 13(4):407-21.
Roepstorff C, Thiele M, Hillig T, Pilegaard H, Richter EA, Wojtaszewski JF, et al. Higher skeletal muscle α2 AMPK activation and lower energy charge and fat oxidation in men than in women during submaximal exercise. J Physiol. 2006; 574(1): 125-38.
Canali ES, Kruel LFM. Respostas hormonais ao exercício. Rev Paul Educ Fís. 2001; 15(2):141-53.
Horowitz JF, Klein S. Lipid metabolism during endurance exercise. Am J Clin Nutr. 2000; 72(2):558S-63S.
Ribeiro BG, Pierucci APTR, Soares EA, Carmo MGT. A influência dos carboidratos no desempenho físico. Rev Bras Med Esporte. 1998; 4(6):197-202.
Ferreira AMD, Ribeiro BG, Soares EA. Consumo de carboidratos e lipídeos no desempenho em exercícios de ultra-resistência. Rev Bras Med Esporte. 2001; 7(2):67-74.
Walker JL, Heigenhauser GJF, Hultman E, Spriet LL. Dietary carbohydrate, muscle glycogen content, and endurance performance in well-trained women. J Appl Physiol. 2000; 88(6):2151-8.
Andrews JL, Sedlock DA, Flynn MG, Navalta JW, Ji H. Carbohydrate loading and supplementation in endurance-trained women runners. J Appl Physiol. 2003; 95(2):584-90.
Wallis GA, Dawson R, Achten J, Webber J, Jeukendrup AE. Metabolic responses to carbohydrate ingestion during exercise in males and females. Am J Physiol Endocrinol Metab. 2005; 290(4):E708-15.
Tarnopolsky MA. Females and males: should nutritional recommendations be gender specific? Sportmedizin und Sporttraumatologie. 2003; 51(1):39-46.
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