Stunting and wasting in children and adolescents with sickle cell disease
Keywords:
Adolescent, Sickle cell anemia, Child, Sickle cell disease, Nutritional statusAbstract
Objective
This study assessed the anthropometric status of children and adolescents with sickle cell disease seen at a pediatric hospital in Rio de Janeiro county, Brazil.
Methods
This cross-sectional study collected data from medical records, which included anthropometric, sociodemographic, clinical, and hematological measurements from the last medical appointment in 2006.
Results
The study comprised 161 children and adolescents of which 15.5% were stunted (height-for-age <-2 Z-scores) and 5.7% were wasted (body mass index-for-age <-2 Z-scores). Children with low birth weight and those whose caregivers did not live with a partner had lower height-for-age Z-scores than children with appropriate birth weight (p=0.030) and those whose caregivers lived with a partner (p=0.003), respectively.
Conclusion
Children and adolescents with sickle cell disease showed a higher prevalence of stunting and wasting than the general population, and low birth weight and caregivers who did not live with a partner were associated with smaller height.
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References
Loureiro MM, Rozenfeld S. Epidemiologia de internações por doenças falciformes no Brasil. Rev Saúde Pública. 2005; 39(6):943-9. doi: 10.1590/ S0034-89102005000600011.
Lobo CLC, Bueno LM, Moura P, Ogeda LL, Castilho S, Carvalho SMF. Triagem neonatal para hemoglobinopatias no Rio de Janeiro, Brasil. Rev Panam Salud Pública. 2003; 1(2-3):154-9. doi: 10.1590/S1020-4 9892003000200018.
Di Nuzzo DVP, Fonseca SF. Anemia falciforme e infecções. J Pediatr. 2004; 80(5):347-54. doi: 10.15 90/S0021-75572004000600004.
Alves AL. Estudo da mortalidade por anemia falciforme. Inf Epidemiol SUS. 1996; 5(4):45-53.
American Academy of Pediatrics. Committee on Genetics. Health supervision for children with sickle cell disease. Pediatrics. 2002; 109(3):526-35. doi: 10.1542/peds.109.3.526
Carneiro J, Murad Y. Crescimento e desenvolvimento. In: Manual de diagnóstico e tratamento para doenças falciformes. Brasília: Agência Nacional de Vigilância Sanitária; 2002. p.77-82.
Singhal A, Davies P, Wierenga K JJ, Thomas P, Grahanis. Is there an energy deficiency in homozygous sickle cell disease? Am J Clin Nutr. 1997; 66(2):386-90
Braga JAP, Kerbauy J, Fisberg M. Zinc, copper and iron and their interrelations in the growth of sickle cell patients. Arch Latin Nutr. 1995; 45(3):198-203.
Barden EM, Kawchak DA, Ohene-Frempong K, Stallings V, Zemel B. Body composition in children with sickle cell disease. Am J Clin Nutr. 2002; 76: 218-25.
Zemel BS, Kawchak DA, Fung EB, Frempong KO, Staliings VA. Effect of zinc supplementation on growth and body composition in children with sickle cell disease. Am J Clin Nutr. 2002; 75:300-7.
Zemel BS, Kawchak DA, Ohene-Frempong K, Schall JI, Stallings VA. Effects of delayed pubertal development, nutritional status, and disease severity on longitudinal patterns of growth failure in children with sickle cell disease. Pediatrics Res. 2007; 61(5):607-13.
World Health Organization. The WHO child growth standards. Geneva: WHO; 2006 [cited 2007 Jun 24]. Available from: <http://www.who.int/childgrowth/standards>.
World Health Organization. Growth reference data for 5-19 years: WHO Reference 2007. Geneva: WHO; 2007. [cited 2007 Jun 24]. Available from: <http://www.who.int/growthref/en/>.
World Health Organization. Training course on child growth assessment. Version 1. Geneva: WHO; 2006 [cited 2007 Jun 24]. Available from: <http://www.who.int/childgrowth/training/Interpreting.pdf>
Miller O, Gonçalves RR. Laboratório para o clínico. 8th ed. Rio de Janeiro: Atheneu; 1999.
World Health Organization. Iron deficiency anaemia assessment, prevention, and control: a guide for programme managers. Geneva: WHO; 2001
Yip R, Johnson C, Dallman PR. Age-related changes in laboratory values used in the diagnosis of anemia and iron deficiency. Am J Clin Nutr. 1984; 39:427-36.
Neto GCG, Pitombeira MS. Aspectos moleculares da anemia falciforme. J Bras Patol Med Lab. 2003; 39(1):51-3.
Programa Nacional de Controle da Qualidade. Valores normais hemogramas. [acesso: 2007 mar. 27]. Disponível em: <http://www.pncq.org.br/biblioteca/valores_normais_hemograma.pdf>
Instituto Brasileiro de Geografia e Estatística. Pesquisa de orçamentos familiares 2002-2003: tabelas 7-13. Brasília: IBGE; 2003 [acesso 2007 mar 27]. Disponível em: <http://www.ibge.gov.br>.
Sociedade Civil Bem-Estar Familiar no Brasil 1996. Pesquisa Nacional de Demografia e Saúde. Rio de Janeiro: Bemfam; 1996 [acesso 2008 jan 1]. Disponível em: <http://dtr2004.saude.gov.br>.
Rodrigues CSC, Lamarca FP, Carvalho CNM, Oliveira CL, Rocha FZ, Marchon VSS, et al. Avaliação antropométrica de admissão em crianças com anemia falciforme internadas na enfermaria de pediatria do hospital Universitário Pedro Ernesto. Nutr Pauta. 2005; 7/8:25-8
Silva CM, Viana MB. Growth deficits in children with sickle cell disease. Arch Med Res. 2002; 33(3): 308-12. doi:10.1016/S0188-4409(01)00360-5.
Al-Saqladi AW, Bin-Gadeen HA, Brabin BJ. Growth in children and adolescents with sickle cell disease in Yemen. Ann Trop Paediatr. 2010; 30(4):287-98. doi:10.1179/146532810X12858955921113.
Buison AM, Kawchak DA, Schall JI, OheneFrempong K, Stallings VA, Leonard MB, et al. Bone area and bone mineral content deficits in children with sickle disease. Pediatrics. 2005; 116(4):943-9. doi: 10.1542/peds.2004-2582.
Al-Saqladi AW, Cipolotti R, Fijnvandraat K, Brabin BJ. Growth and nutritional status of children with homozygous sickle cell disease. Ann Trop Paediatr. 2008; 28(3):165-89. doi: 10.1179/146532808X335624.
Brasil. Ministério da Saúde. Fundamentos técnicocientíficos e orientações práticas para o acompanhamento do crescimento e desenvolvimento - Parte 1: crescimento. Brasília: MS; 2001 [acesso: 2008 jan 7]. Disponível em: .
Puffer ES, Schatz JC, Roberts CW. Relationships between somatic growth and cognitive functioning in young children with sickle cell disease. J Pediatr Psychol. 2010; 35(8):892-304
Carvalhaes MABL, Benício MHDA. Capacidade materna de cuidar e desnutrição infantil. Rev Saúde Pública. 2002; 36(2):188-97.
. Silva FG, Tavares-Neto J. Avaliação dos prontuários médicos de hospitais de ensino do Brasil. Rev Bras Educ Med. 2007; 31(2):113-26. doi: 10.1590/S010 0-55022007000200002.
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Copyright (c) 2023 Karen Cordovil Marques de SOUZA, Paulo Ivo Cortez de ARAÚJO, Paulo Roberto Borges SOUZA-JUNIOR, Elisa Maria de Aquino LACERDA
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