Phase angle as a screening method for sarcopenia in community-dwelling older adults

Authors

Keywords:

Aged, Electric Impedance, Sarcopenia

Abstract

 

 Objective

We investigated the utility of the phase angle as a screening tool for sarcopenia.

Methods

We performed a cross-sectional study that included 169 active community-dwelling elderly women. The phase angle was determined using tetrapolar bioelectrical impedance, and sarcopenia was diagnosed based on skeletal muscle mass, muscle strength, and physical performance using bioelectrical impedance analysis, a handheld dynamometer, and the gait speed test, respectively. Receiver operating characteristic curve analysis was performed to investigate the role of the phase angle as a predictor of sarcopenia.

Results

The prevalence of sarcopenia was 12.4%. The median phase angle was 5.30°; elderly women with sarcopenia had lower phase angles than those without sarcopenia (p=0.006). The phase angle cutoff for the detection of sarcopenia was ≤5.15°, with an area under the curve of 0.685, sensitivity 81.0%, specificity 60.8%, and accuracy 63.31%. Elderly women with a low phase angle show a high risk of presenting with reduced muscle mass.

Conclusion

The phase angle was shown to be a useful screening tool in elderly women with sarcopenia.

Downloads

Download data is not yet available.

References

Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(1):16-31. https://doi.org/10.1093/ageing/afy169

Peng TC, Chen WL, Wu LW, Chang YW, Kao TW. Sarcopenia and cognitive impairment: A systematic review and meta-analysis. Clin Nutr. 2020;39(9):2695-701. https://doi.org/10.1016/j.clnu.2019.12.014

Yeung SSY, Reijnierse EM, Pham VK, Trappenburg MC, Lim WK, Meskers CGM et al. Sarcopenia and its association with falls and fractures in older adults: a systematic review and meta-analysis. J Cachexia Sarcopenia Muscle. 2019;10(3):485-500. https://doi.org/10.1002/jcsm.12411

Tsekoura M, Kastrinis A, Katsoulaki M, Billis E, Gliatis J. Sarcopenia and its impact on quality of life. Adv Exp Med Biol. 2017;987:213-8. https://doi.org/10.1007/978-3-319-57379-3_19

Kilic MK, Kizilarslanoglu MC, Arik G, Bolayir B, Kara O, Dogan Varan H, et al. Association of bioelectrical impedance analysis-derived phase angle and sarcopenia in older adults. Nutr Clin Pract. 2017;32(1):103-9. https://doi. org/10.1177/0884533616664503

Mattiello R, Amaral MA, Mundstock E, Ziegelmann PK. Reference values for the phase angle of the electrical bioimpedance: systematic review and meta-analysis involving more than 250,000 subjects. Clin Nutr. 2020;39(5):1411-7. https://doi.org/10.1016/j.clnu.2019.07.004

Garlini LM, Alves FD, Ceretta LB, Perry IS, Souza GC, Clausell NO. Phase angle and mortality: a systematic review. Eur J Clin Nutr. 2019;73:495-508. https://doi.org/10.1038/s41430-018-0159-1

Ferreira AJF, Eickemberg M, Carneiro AKR, Barreto JMB, Ramos LB. Phase angle in institutionalized elderly brazilians. J Nurs Home Res. 2017;3:38-42. https://doi.org/10.14283/jnhrs.2017.6

Santana NM, Pinho CPS, Silva CP, Santos NF, Mendes RML. phase angle as a sarcopenia marker in hospitalized elderly patients. Nutr Clin Pract. 2018;33(2):232-7. https://doi.org/10.1002/ncp.10016

Alexandre TS, Duarte YA, Santos JL, Wong R, Lebrão ML. Prevalence and associated factors of sarcopenia among elderly in Brazil: findings from the SABE study. J Nutr Health Aging. 2014;18(3):284-90.

Baumgartner RN, Chumlea WC, Roche AF. Bioelectric impedance phase angle and body composition. Am J Clin Nutr. 1988;48(1):16-23. https://doi.org /10.1093/ajcn/48.1.16

Kyle UG, Bosaeus I, Lorenzo AD, Deurenberg P, Elia M, Gómez JM, et al. Bioelectrical impedance analysis part I: review of principles and methods. Clin Nutr. 2004;23(5):1226-43. https://doi.org/10.1016/j.clnu.2004.06.004

Fess EE. Grip strength. In: American Society of Hand Therapists [editor]. Clinical assessment recommendations. 2nd. ed. Garner, NC: Society. 1992;41-5.

Janssen I, Heymsfield SB, Baumgartner RN, Ross R. Estimation of skeletal muscle mass by bioelectrical impedance analysis. J Appl Physiol. 2000;89(2):465-71. https://doi.org/10.1152/jappl.2000.89.2.465

Lauretani F, Russo CR, Bandinelli S, Bartali B, Cavazzini C, Di Iorio A, et al. Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia. J Appl Physiol. 2003;95(5):1851-60. https://doi. org/10.1152/japplphysiol.00246.2003

Yamada M, Kimura Y, Ishiyama D, Nishio N, Otobe Y, Tanaka T, et al. Phase angle is a useful indicator for muscle function in older adults. J Nutr Health Aging. 2019;23(3):251-5. https://doi.org/10.1007/s12603-018-1151-0

Gonzalez MC, Barbosa-Silva TG, Bielemann RM, Gallagher D, Heymsfield SB. Phase angle and its determinants in healthy subjects: influence of body composition. Am J Clin Nutr. 2016;103(3):712-6. https://doi.org/10.3945/ ajcn.115.116772

Mulasi U, Kuchnia AJ, Cole AJ, Earthman CP. Bioimpedance at the bedside: current applications, limitations, and opportunities. Nutr Clin Pract. 2015;30(2):180-93. https://doi.org/10.1177/0884533614568155

Tomeleri CM, Cavalcante EF, Antunes M, Nabuco HCG, Souza MF, Teixeira DC, et al. Phase angle is moderately associated with muscle quality and functional capacity, independent of age and body composition in older women. J Geriatr Phys Ther. 2019;42(4):281-6. https://doi.org/10.1519/JPT.0000000000000161

Souza MF, Tomeleri CM, Ribeiro AS, Schoenfeld BJ, Silva AM, Sardinha LB, et al. Effect of resistance training on phase angle in older women: a randomized controlled trial. Scand J Med Sci Sports. 2017;27(11):1308-16. https://doi.org/ 10.1111/sms.12745

Ribeiro AS, Schoenfeld BJ, Souza MF, Tomeleri CM, Silva AM, Teixeira DC, et al. Resistance training prescription with different load-management methods improves phase angle in older women. Eur J Sport Sci. 2017;17(7):913-21. https://doi.org/10.1080/17461391.2017.1310932

Cunha PM, Tomeleri CM, Nascimento MAD, Nunes JP, Antunes M, Nabuco HCG, et al. Improvement of cellular health indicators and muscle quality in older women with different resistance training volumes. J Sports Sci. 2018;36(24):2843-8. https://doi.org/10.1080/02640414.2018.1479103

Pessoa DF, Branco FMS, Reis AS, Limirio LS, Borges LP, Barbosa CD, et al. Association of phase angle with sarcopenia and its components in physically active older women. Aging Clin Exp Res. 2020;32:1469-75. https://doi.org/10.1007/ s40520-019-01325-0

Bittencourt DCD, Schieferdecker MEM, Macedo DS, Biesek S, Gomes AS, Rabito EI. Phase angle reflects loss of functionality in older women. J Nutr Health Aging. 2020;24(3):251-4. https://doi.org/10.1007/s12603-020-1324-5

Campa F, Silva AM, Toselli S. Changes in phase angle and handgrip strength induced by suspension training in older women. Int J Sports Med. 2018;39(6):442-9. https://doi.org/10.1055/a-0574-3166

Matias CN, Nunes CL, Francisco S, Tomeleri CM, Cyrino ES, Sardinha LB, et al. Phase angle predicts physical function in older adults. Arch Gerontol Geriatr. 2020;90:104151. https://doi.org/10.1016/j.archger.2020.104151

Downloads

Published

2023-07-28

How to Cite

SANTIAGO, L. B., RORIZ, A. K. C. ., OLIVEIRA, C. C. de ., OLIVEIRA, T. M. de, CONCEIÇÃO-MACHADO, M. E. P. da ., & RAMOS, L. B. (2023). Phase angle as a screening method for sarcopenia in community-dwelling older adults. Brazilian Journal of Nutrition, 35. Retrieved from https://puccampinas.emnuvens.com.br/nutricao/article/view/8985

Issue

Section

ORIGINAL ARTICLE