Papel da vitamina D no lúpus eritematoso sistêmico
Palabras clave:
Lúpus eritematoso sistêmico, Sistema imune, Vitamina DResumen
Além do papel na homeostase do cálcio, acredita-se que a forma ativa da vitamina D apresente efeitos imunomoduladores, suprimindo ou ativando o sistema imune. Estudos recentes têm relacionado a deficiência ou a insuficiência de vitamina D a várias doenças autoimunes, como lúpus eritematoso sistêmico, artrite reumatoide, diabetes Mellitus tipo 1 e esclerose múltipla. Dessa forma, o presente trabalho buscou descrever o metabolismo da vitamina D e suas funções, enfatizando sua ação no sistema imune bem como a participação no lúpus eritematoso sistêmico. Todas as evidências encontradas estão voltadas para a relação entre baixos níveis de vitamina D e manifestações clínicas do lúpus eritematoso sistêmico, porém ainda não está definido se a suplementação ou recuperação desses níveis possa influir na atividade da doença. Dessa forma, há necessidade de mais estudos para avaliar os possíveis benefícios terapêuticos da suplementação de vitamina D no lúpus eritematoso sistêmico.
Citas
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Derechos de autor 2023 Thaisa de Mattos TEIXEIRA, Célia Lopes da COSTA
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
