Body composition of women with and without dynapenia defined by different cut-off points
Keywords:
Adipose tissue, Muscle weakness, Postmenopause, Skeletal musclesAbstract
Objective
To compare body composition of postmenopausal women with and without dynapenia, defined by different cut-off points.
Methods
Body composition was assessed by electrical bioimpedance and the nutritional status by the body mass index. Dynapenia was diagnosed according to handgrip strength, using the following cut-off points: handgrip strength <16kgf and <20 kgf.
Results
A total of 171 women (50 to 92 years of age) participated in the investigation. The mean age of non-dynapenic and dynapenic women (handgrip strength <20kgf) was 69.4±8.2 and 74.5±8.2 years, respectively. The mean age of women with dynapenia (handgrip strength <16kgf) was 75.0±10.1 years and non-dynapenic women, 71.1±8.2 years. It was found that dynapenic women, with handgrip strength <20 and <16kgf, had an average of 2.38 and 2.47kg less muscle mass respectively, when compared to non-dynapenic women (p<0.05). However, there was no difference in muscle mass between the different dynapenic groups. Non-dynapenic women (handgrip strength ≥20kgf) had more total (3.55kg) and central fat (1.47kg) (p<0.05).
Conclusion
Dynapenic women, diagnosed considering both cutoff points, had less total and segmental muscle mass compared to non-dynapenic women. In addition, dynapenic women with handgrip strength <20kgf had lower total and trunk adiposity.
References
Chidi-Ogbolu N, Baar K. Effect of estrogen on musculoskeletal performance and injury risk. Front in Physiol. 2018;9:1834. https://doi.org/10.3389/fphys.2018.01834
Karvonen-Gutierrez C, Kim C. Association of mid-life changes in body size, body composition and obesity status with the menopausal transition. Healthcare. 2016;4(3):42. https://doi.org/10.3390/healthcare4030042
Bacon JL. The menopausal transition. Obstet Gynecol Clin of North Am. 2017;44(2):285-96. https://doi.org/10.1016/j.ogc.2017.02.008
Clark BC, Manini TM. Sarcopenia≠dynapenia. J Gerontol Series A: Biol Sci Med Sci. 2008;63(8):829-34.
Marques KM, Previato MNF, Freitas TI, Goulart RMM, Aquino RC, Previdell AN. Evaluation of dynapenia in the elderly in São Caetano do Sul, São Paulo, Brazil. Fisio Mov. 2019;32e003218. https://doi.org/10.1590/1980-5918.032.AO18
Alexandre TS, Duarte YAO, Santos JLF, Lebrão ML. Prevalência e fatores associados à sarcopenia, dynapenia e sarcodynapenia em idosos residentes no Município de São Paulo-Estudo SABE. Rev Bra Epidemiol. 2019;21:180009.
Tieland M, Trouwborst I, Clark BC. Skeletal muscle performance and ageing. J Cachexia Sarcopenia Muscle. 2018;9(1):3-19. https://doi.org/10.1002/jcsm.12238
Aubertin-Leheudre M, Anton S, Beavers DP, Manini TM, Fielding R, Newman A, et al. Dynapenia and metabolic health in obese and nonobese adults aged 70 years and older: the LIFE Study. J Am Med Dir Assoc. 2017. https://doi.org/10.1016/j.jamda.2016.10.001
Tagliaferri C, Wittrant Y, Davicco MJ, Walrand S, Coxam V. Muscle and bone, two interconnected tissues. Ageing Res Rev. 2015;21:55-70. https://doi.org/10.1016/j.arr.2015.03.002
Hamad B, Basaran S, Benlidayi IC. Osteosarcopenia among postmenopausal women and handgrip strength as a practical method for predicting the risk. Aging Clin Exp Res. 2019;1-8. https://doi.org/10.1007/s40520-019-01399-w
Dulac M, Boutros GEH, Pion C, Barbat-Artigas S, Gouspillou G, Aubertin-Leheudre M. Is handgrip strength normalized to body weight a useful tool to identify dynapenia and functional incapacity in post-menopausal women? Bra J of Phys Ther. 2016;20(6):510-6. https://doi.org/10.1590/bjpt-rbf.2014.0184
Iwamura M, Kanauchi M. A cross-sectional study of the association between dynapenia and higher-level functional capacity in daily living in community-dwelling older adults in Japan. Bmc Geriatr. 2017;17(1):1. https://doi.org/10.1186/s12877-016-0400-5
Scott D, Daly RM, Sanders KM, Ebeling PR. Fall and fracture risk in sarcopenia and dynapenia with and without obesity: the role of lifestyle interventions. Curr Osteoporos Rep. 2015;13(4): 235-44. https://doi.org/10.1007/s11914-015-0274-z
García-Hermoso A, Cavero-Redondo I, Ramírez-Vélez R, Ruiz JR, Ortega FB, Lee DC, et al. Muscular strength as a predictor of allcause mortality in an apparently healthy population: a systematic review and meta-analysis of data from approximately 2 million men and women. Arch Phys Med Rehabil. 2018;99(10):2100-13. https://doi.org/10.1016/j.apmr.2018.01.008
Volaklis KA, Halle M, Meisinger C. Muscular strength as a strong predictor of mortality: a narrative review. Eur J Intern Med. 2015;26(5):303-10. https://doi.org/10.1016/j.ejim.2015.04.013
Li R, Xia J, Zhang XI, Gathirua-Mwangi WG, Guo J, Li Y, et al. Associations of muscle mass and strength with all-cause mortality among US older adults. Med Sci Sports Exerc. 2018;50(3):458-67. https://doi.org/10.1249/MSS.0000000000001448
Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(1):16-31. https://doi.org/10.1093/ageing/afz046
Lauretani F, Russo CR, Bandinelli S, Bartali B, Cavazzini C, Di Iorio A, et al. Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia. J Appl Physiol. 2003;95(5):1851-60. https://doi.org/10.1152/japplphysiol.00246.2003
Dodds RM, Syddall HE, Cooper R, Benzeval M, Deary IJ, Dennison EM, et al. Grip strength across the life course: normative data from twelve British studies. Plos One. 2014;9(12):e113637. https://doi.org/10.1371/journal.pone.0113637
Frisancho AR. New standards of weight and body composition by frame size and height for assessment of nutritional status of adults and the elderly. Am J Clin Nutr. 1984;40(4):808-19. https://doi.org/10.1093/ajcn/40.4.808
Associação Brasileira para o Estudo da Obesidade e da Síndrome Metabólica. Diretrizes brasileiras de obesidade. 4a. ed. São Paulo: Associação; 2016 [cited: 2019 June 11]. Available from: https://abeso.org.br/wp-content/uploads/2019/12/Diretrizes-Download-Diretrizes-Brasileiras-de-Obesidade-2016.pdf
Figueiredo IM, Sampaio RF, Mancini MC, Silva CM, Souza MAP. Teste de força de preensão utilizando o dinamômetro Jamar. Acta Fisiátrica. 2007;14(2):104-10. https://doi.org/10.5935/0104-7795.20070002
Filion ME, Barbat-Artigas S, Dupontgand S, Fex A, Karelis AD, Aubertin-Leheudre M. Relationship between protein intake and dynapenia in postmenopausal women. J Nutr Health Aging. 2012;16(7):616-9. https://doi.org/10.1007/s12603-012-0054-8
Barbat-Artigas S, Dupontgand S, Fex A, Karelis AD, Aubertin-Leheudre M. Relationship between dynapenia and cardiorespiratory functions in healthy postmenopausal women: novel clinical criteria. Menopause. 2011;18(4):400-5. https://doi.org/10.1097/gme.0b013e3181f7a596
Mitchell WK, Williams J, Atherton P, Larvin M, Lund J, Narici M. Sarcopenia, dynapenia, and the impact of advancing age on human skeletal muscle size and strength; a quantitative review. Front in Physiol. 2012;3:260. https://doi.org/10.3389/fphys.2012.00260
Tessier AJ, Wing SS, Rahme E, Morais JA, Chevalier S. Physical function-derived cut-points for the diagnosis of sarcopenia and dynapenia from the Canadian longitudinal study on aging. J Cachexia Sarcopenia Muscle. 2019;10(5):985-99. https://doi.org/10.1002/jcsm.12462
Greendale GA, Sternfeld B, Huang M, Han W, Karvonen-Gutierrez C, Ruppert K, et al. Changes in body composition and weight during the menopause transition. JCI Insight. 2019;4(5):124865. https://doi.org/10.1172/jci.insight.124865
Mulligan R, Gilmer-Scott M, Kouchel D, Nickelson D, Safavi A, Drickamer M, et al. Unintentional weight loss in older adults: a geriatric interprofessional simulation case series for health care providers. MedEdPORTAL. 2017;20;13:10631. https://doi.org/10.15766/mep_2374-8265.10631
Ely BR, Clayton ZS, McCurdy CE, Pfeiffer J, Minson CT. Meta-inflammation and cardiometabolic disease in obesity: Can heat therapy help? Temperature (Austin). 2017;10;5(1):9-21. https://doi.org/10.1080/23328940.2017.1384089
Cooke AA, Connaughton RM, Lyons CL, McMorrow AM, Roche HM. Fatty acids and chronic low grade inflammation associated with obesity and the metabolic syndrome. Eur J Pharmacol. 2016;15;785:207-14. https://doi.org/10.1016/j.ejphar.2016.04.021
Martyniak K, Masternak MM. Changes in adipose tissue cellular composition during obesity and aging as a cause of metabolic dysregulation. Exp Gerontol. 2017;94:59-63. https://doi.org/0.1016/j.exger.2016.12.007
Poledne R, Králová Lesná I, Čejková S. Adipose tissue and atherosclerosis. Physiol Res. 2015;64(Suppl3):S395-402. https://doi.org/10.33549/physiolres.933152
Gonçalves TJMG, Horie LMH, Gonçalves SEAB, Bacchi MK, Bailer MC, Barbora Silva TG. Diretriz BRASPEN de terapia nutricional no envelhecimento. Braspen J. 2019 [cited: 2019 June 11];34(3):1-68. Available from: https://nutritotal.com.br/pro/wp-content/uploads/sites/3/2019/11/Material-1-diretriz-TN-no-envelhecimento.pdf
Bull FC, Al-Ansari SS, Biddle S, Borodulin K, Buman MP, Cardon G, et al. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. Br J Sport Med. 2020;54(24):1451-62. https://doi.org/10.1136/bjsports-2020-102955
Fragala MR, Cadore EL, Dorgo S, Izquierdo M, Kraemer WJ, Peterson MD, et al. Resistance training for older adults: position statement from the national strength and conditioning association. J Strength Cond Res. 2019;33(8):2019-52. https://doi.org/10.1519/JSC.0000000000003230
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Lucas dos SANTOS, Camille Giehl Martins MIRANDA, Tasso Carvalho Barberino de SOUZA, Thais Alves BRITO, Marcos Henrique FERNANDES, José Ailton Oliveira CARNEIRO
This work is licensed under a Creative Commons Attribution 4.0 International License.
