Dietary total antioxidant capacity and its association with anthropometric, biochemical, and functional parameters in chronic kidney disease patients on hemodialysis

Authors

  • Danielle Cristina Guimarães da SILVA Universidade Federal do Oeste da Bahia
  • Fabrícia Geralda FERREIRA Escola Preparatória de Cadetes do Ar
  • Thailane Carvalho dos SANTOS Universidade Federal do Oeste da Bahia
  • Joice Natielle Mariano de ALMEIDA Universidade Federal do Oeste da Bahia
  • Ellen de Souza ALMEIDA Universidade Federal do Oeste da Bahia

Keywords:

Anthropometry, Antioxidants, Food Consumption, Renal Dialysis

Abstract

Objective
To investigate the association of dietary total antioxidant capacity with anthropometric, functional, and biochemical parameters in chronic kidney disease patients on hemodialysis.

Methods
This is a cross-sectional study of hemodialysis patients in Western Bahia. A structured questionnaire, three 24-hour dietary recalls, anthropometric measurements and clinical and biochemical records were used for data collection. Dietary total antioxidant capacity was estimated using 24-hour dietary recalls data. A database of ferric reducing antioxidant power values for foods was used to evaluate the dietary total antioxidant capacity. Multiple linear regression was applied to assess the relationship between dietary total antioxidant capacity and anthropometric, functional, and biochemical parameters.
Results
A total of 97 patients were evaluated, of which 57.7% were men and 57.7% were aged between 36 and 59 years. After adjusting for gender, education level, and socioeconomic level, inverse associations were found between dietary total antioxidant capacity and body mass index (p=0.008). Handgrip strength (p=0.037) and serum albumin concentration (p=0.047) were positively associated with dietary total antioxidant capacity.
Conclusion
High dietary total antioxidant capacity is associated with low body mass index, high handgrip strength, and high serum albumin concentration in chronic kidney disease patients undergoing hemodialysis.

References

Oliveira CM, Santos EBA, Bermude BEBV, Ferreira LR, Tizzot EA, Mourão Júnior CA. A importância do médico de atenção primária no rastreamento e diagnóstico precoce da doença renal crônica. Rev Ciênc Saúde. 2019;9(2):4-8. https://doi.org/10.21876/rcshci.v9i2.728

Monteiro MAC, Sousa G, Santos LS, Studart RM, Bonfim IM, Guerra DR. Chronic renal disease: characteristics of patients waiting for renal transplantation. Rev Enferm UFPI. 2018;7(2):18-22. https://doi.org/10.26694/2238-7234.7218-22

Amaral TLM, Amaral CA, Vasconcellos, MTL, Monteiro GTR. Doença renal crônica em adultos jovens de Rio Branco, Acre: inquérito de base populacional. Ciênc Saúde Coletiva. 2021;26(1):339-50. https://doi.org/10.1590/1413-81232020261.22402018

Sesso RC, Lopes AA, Thomé FS, Lugon JR, Martins CT. Brazilian chronic dialysis survey 2016. J Bras Nefrol. 2017;39(3):261-66. https://doi.org/10.5935/0101-2800.20170049

Marinho AWGB, Penha AP, Silva MT, Galvão TF. Prevalence of chronic renal disease among Brazilian adults: a systematic review. Cad Saúde Coletiva. 2017;25(3):379-88. https://doi.org/10.1590/1414-462x201700030134

Pedraza-Chaverri J, Sánchez-Lozada LG, Osorio-Alonso H, Tapia E, Scholze A. New pathogenic concepts and therapeutic approaches to oxidative stress in chronic kidney disease. Oxid Med Cell Longev. 2016;2016:6043601. https://doi.org/101155/2016/6043601

Podkowińska A, Formanowicz D. Chronic kidney disease as oxidative stress- and inflammatory-mediated cardiovascular disease. Antioxidants. 2020;9(8):752. https://doi.org/10.3390/antiox9080752

Liakopoulos V, Roumeliotis S, Gorny X, Dounousi E, Mertens PR. Oxidative stress in hemodialysis patients: a review of the literature. Oxid Med Cell Longev. 2017;2017:3081856. https://doi.org/101155/2017/30811856

Wang Y, Chun OK, Song WO. Plasma and dietary antioxidant status as cardiovascular disease risk factors: a review of human studies. Nutrients. 2013;5(8):2969-3004. https://doi.org/10.3390/nu5082969

Hasanuzzaman M, Bhuyan MHMB, Zulfiqar F, Raza A, Mohsin SM, Mahmud JA, Fujita M, Fotopoulos V. Reactive Oxygen Species and Antioxidant Defense in Plants under Abiotic Stress: Revisiting the Crucial Role of a Universal Defense Regulator. Antioxidants. 2020;9(8):681. https://doi.org/10.3390/antiox9080681

Nascimento-Souza MA, Paiva PG, Martino HSD, Ribeiro AQ. Dietary total antioxidant capacity as a tool in health outcomes in middle-aged and older adults: A systematic review. Crit Rev Food Sci Nutr. 2018;58(6):905-12. https://doi.org/10.1080/10408398.2016.1230089

Pellegrini N, Vitaglione P, Granato D, Fogliano V. Twenty-five years of total antioxidant capacity measurement of foods and biological fluids: merits and limitations. J Sci Food Agric. 2018;100(4):5064-78. https://doi.org/10.1002/jsfa.9550

Puchau B, Zulet M, Echávarri AG, Hermsdorff HHM, Martinez JA. Dietary total antioxidant capacity: a novel indicator of diet quality in healthy Young adults. J Am Coll Nutr. 2009;28(6):648-56. https://doi.org/10.1080/07315724.2009.107199797

Dennis JM, Witting PK. Protective role for antioxidants in acute kidney disease. Nutrients. 2017;9(7):718. https://doi.org/10.3390/nu9070718

Liakopoulos V, Roumeliotis S, Bozikas A, Eleftheriadis T, Dounousi E. Antioxidant supplementation in renal replacement therapy patients: is there evidence? Oxid Med Cell Longev. 2019;2019:9109473. https://doi.org/10.1155/2019/9109473

Small DM, Coombes JS, Bennett N, Johnson DW, Gobe GC. Oxidative stress, anti-oxidant therapies and chronic kidney disease. Nephrology (Carlton, Vic). 2012;17(4):311-21. https://doi.org/10.1111/j.1440-1797.2012.01572.x

Huang D. Dietary antioxidants and health promotion. Antioxidants. 2018;7(1):9. https://doi.org/10.3390/antiox701000918. Lima LF, Ghetti FF, Hermsdorff HHM, Oliveira DG, Teixeira G, Ferreira LEVVC, et al. Dietary total antioxidant capacity is positively associated with muscular strength in cirrhotic outpatients: a cross-sectional study. J Hum Nutr Diet. 2019;33:78-85. https://doi.org/10.1111/jhn.12698

Asghari G, Yuzbashian E, Shahemi S, Gaeini Z, Mirmiran P, Azizi F. Dietary total antioxidant capacity and incidence of chronic kidney disease in subjects with dysglycemia: Tehran Lipid and Glucose Study. Eur J Nutr. 2018;57(7):2377-85. https://doi.org/10.1007/s00394-017-1511-2

Abbasi M, Daneshpour MS, Hedayati M, Mottaghi A, Pourvali K, Azizi F. Dietary total antioxidant capacity and the risk of chronic kidney disease in patients with type 2 diabetes: a nested case-control study in the tehran lipid glucose study. J Ren Nutr. 2019;29(5):394-98. https://doi.org/10.1053/j.jrn.2018.11.008

Associação Brasileira de Empresas de Pesquisa. Critério de Classificação econômica Brasil. São Paulo: Associação; 2016 [cited 2020 Jul 19]. Available from: http://www.abep.org/criterio-brasil

Associação Brasileira para o Estudo da Obesidade e Síndrome Metabólica. Diretrizes Brasileiras de Obesidade. 4a. ed. São Paulo: Associação; 2016.

Monteiro JP, Pfrimer K, Tremeschin MH, Molina MC, Chiarello P. Consumo Alimentar: Visualizando Porções. Rio de Janeiro, Guanabara Koogan; 2013.

Pinheiro ABV, Lacerda EMA, Benzecry EH, Gomes MCS, Costa VM. Tabela para avaliação de consumo alimentar em medidas caseiras. 5a. ed. São Paulo: Atheneu; 2008.

Carlsen MH, Halvorsen BL, Holte K, Bohn SK, Dragland S, Sampson L, et al. The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide. Nutr J. 2010;9(3). https://doi.org/10.1186/1475-2891-9-3

Santin F, Canella D, Borges C, Lindholm B, Avesani CM. Dietary patterns of patients with chronic kidney disease: the influence of treatment modality. Nutrients. 2019;11(8):1920. https://doi.org/10.3390/nu11081920

Saglimbene VM, Wong G, Ruospo M, Palmer SC, Garcia-Larsen V, Natale P, et al. JC. Fruit and Vegetable Intake and Mortality in Adults undergoing Maintenance Hemodialysis. Clin J Am Soc Nephrol. 2019;14(2):250-60. https://doi.org/10.2215/CJN.08580718

Van der Schaft N, Trajanoska K, Rivadeneira F, Ikram MA, Schoufour JD, Voortman T. Total dietary antioxidant capacity and longitudinal trajectories of body composition. Antioxidants (Basel). 2020;9(8):728. https://doi.org/10.3390/antiox9080728

Ladhani M, Craig JC, Irving M, Clayton PA, Wong G. Obesity and the risk of cardiovascular and all-cause mortality in chronic kidney disease: a systematic review and meta-analysis. Nephrol Dial Transplant. 2017;1;32(3):439-49. https://doi.org/10.1093/ndt/gfw075

Jun M, Venkataraman V, Razavian M, Cooper B, Zoungas S, Ninomiya T, et al. Antioxidants for chronic kidney disease. Cochrane Database Syst Rev. 2012;10:CD008176. https://doi.org/10.1002/14651858.CD008176.pub2

Ling XC, Kuo K. Oxidative stress in chronic kidney disease. Ren Replace Ther. 2018;4:53. https://doi.org/10.1186/s41100-018-0195-2

Cesare MM, Felice F, Santini V, Di Stefano R. Antioxidants in sport sarcopenia. Nutrients. 2020;12(9):2869. http://doi.org/10.3390/nu12092869

Oliveira DG, Guetti FF, Moreira APB, Hermsdorff HHM, Oliveira JM, Ferreira LEVVC. Association between dietary total antioxidant capacity and hepatocellular ballooning in nonalcoholic steatohepatitis: a cross-sectional study. Eur J Nutr. 2019;58(6):2263-70. https://doi.org/10.1007/s00394-018-1776-0

Beetch M, Harandi-Zadeh S, Shen K, Lubecka K, Kitts DD, O’Hagan HM, Stefanska B. Dietary antioxidants remodel DNA methylation patterns in chronic disease. Br J Pharmacol. 2020;177(6):1382-408. https://doi.org/10.1111/bph.14888

Sahni N, Gupta KL, Rana SV, Prasad R, Bhalla AK. Intake of antioxidants and their status in chronic kidney disease patients. J Ren Nutr. 2012;22(4):389-99. https://doi.org/10.1053/j.jrn.2011.09.002

Santos AFF. Inadequação do consumo alimentar de nutrients antioxidants em nefropatas crônicos em hemodiálise. Rev Med UFC. 2017;57(2):31-6. https://doi.org/10.20513/2447-6595.2017v57n2p31-36

Maraj M, Kuśnierz-Cabala B, Dumnicka P, Gawlik K, Pawlica-Gosiewska D, Gala-Btadzinska A, et al. Redox balance correlates with nutritional status among patients with end-stage renal disease treated with maintenance hemodialysis. Oxid Med Cell Longev. 2019;10. https://doi.org/10.1155/2019/6309465

Dantas ENA, Silva EB, Silva CP, Oliveira ND, Moura RL, Ponciano CS, et al. Terapia nutricional submetida em pacientes com doença renal crônica. Int J Nutr. 2018;(S01):S24-S327. https://doi.org/10.1055/s-0038-1674306

Gutiérrez OM. Contextual poverty, nutrition, and chronic kidney disease. Adv Chronic Kidney Dis. 2015;22(1):31-8.

https://doi.org/10.1053/j.ackd.2014.05.005

Oliveira APB, Schmidt DB, Amatneeks TM, Santos JC, Cavallet LHR, Michel RB. Qualidade de vida de pacientes em hemodiálise e sua relação com mortalidade, hospitalizações e má adesão ao tratamento. J Bras Nefrol. 2016;38(4):411-20. https://doi.org/10.5935/0101-2800.20160066

Marinho CLA, Oliveira JF, Borges JES, Fernandes FECV, Silva RS. Associação entre características sociodemográficas e qualidade de vida de pacientes renais crônicos em hemodiálise. Rev Cuid. 2018;9(1):2017-29. https://doi.org/10.15649/cuidarte.v9i1.483

Feistauer MAV, Lazaretti AS, Poeta J, Roncada C. Associação entre interleucina-6 e doença renal crônica: uma revisão sistemática. Rev Ciênc Med. 2017;26(3):107-16. https://doi.org/10.24220/2318-0897v26n3a3879

Novaes GM, Silva MJD, Achkar MT, Vilegas W. Compostos antioxidantes e sua importância nos organismos. Rev Univ Vale Rio Verde. 2013;11(2):535-39. http://doi.org/10.5892/ruvrd.v11i2.535539

Rapa SF, DiIorio BR, Campiglia P, Heidland A, Marzocco S. Inflammation and oxidative stress in chronic kidney disease-potential therapeutic role of minerals, vitamins and plant-derived metabolites. Int J Mol Sci. 2020;21(1):263. http://doi.org/10.3390/ijms21010263.

Downloads

Published

2022-07-08

How to Cite

Guimarães da SILVA, D. C. ., FERREIRA, F. G., Carvalho dos SANTOS, T. ., Mariano de ALMEIDA, J. N. ., & de Souza ALMEIDA, E. . (2022). Dietary total antioxidant capacity and its association with anthropometric, biochemical, and functional parameters in chronic kidney disease patients on hemodialysis. Brazilian Journal of Nutrition, 34, 1–10. Retrieved from https://puccampinas.emnuvens.com.br/nutricao/article/view/6296

Issue

Section

ORIGINAL ARTICLE